Saccharomyces Boulardii CNCM I-745 on Intestinal Barrier Function

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

56

Participants

Timeline

Start Date

April 13, 2023

Primary Completion Date

December 30, 2025

Study Completion Date

January 31, 2026

Conditions
Healthy
Interventions
DRUG

Indomethacin

Immediate release oral capsules 50 mg, 3 times a day for 6 days

DIETARY_SUPPLEMENT

S. boulardii CNCM I-745

Two 250 mg capsules orally twice daily for 14 days

DRUG

Placebo

Two 250 mg capsules that contains no active study ingredient orally twice daily for 14 days

Trial Locations (1)

55905

RECRUITING

Mayo Clinic, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mayo Clinic

OTHER

NCT05538247 - Saccharomyces Boulardii CNCM I-745 on Intestinal Barrier Function | Biotech Hunter | Biotech Hunter