LOcoregional vs Systemic Therapy in Patients With BCLC Stage B HCC

PHASE2TerminatedINTERVENTIONAL
Enrollment

1

Participants

Timeline

Start Date

September 27, 2023

Primary Completion Date

June 6, 2025

Study Completion Date

June 6, 2025

Conditions
Hepatocellular Carcinoma
Interventions
DRUG

Atezolizumab and bevacizumab

Atezolizumab will be administered by IV infusion at a fixed dose of 1200 mg on Day 1 of each 21-day cycle and Bevacizumab will be administered by IV infusion at a dose of 15 mg/kg on Day 1 of each 21-day cycle

RADIATION

transarterial chemoembolization (TACE) or transarterial radioembolization (TARE

TACE cycles occur every 8 weeks +/- 7 days OR TARE cycles occur every 12 weeks +/- 7 days

Trial Locations (1)

75390

Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas, Dallas

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

University of Texas Southwestern Medical Center

OTHER

NCT05537402 - LOcoregional vs Systemic Therapy in Patients With BCLC Stage B HCC | Biotech Hunter | Biotech Hunter