Adjuvant Treatment Based on MRD for EGFR Mutant NSCLC

PHASE2RecruitingINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

September 13, 2022

Primary Completion Date

October 1, 2025

Study Completion Date

October 1, 2030

Conditions
MRD
Interventions
GENETIC

Adjuvant treatment for MRD positivity

The MRD positive group would receive icotinib as adjuvant treatment. When the peripheral blood MRD turned negative, the subjects entered the drug withdrawal observation period. When the MRD turned positive again, the subjects resumed icotinib treatment. If EGFR T790M mutation was found, researchers would resume medication and choose osimertinib therapy.

Trial Locations (16)

Unknown

NOT_YET_RECRUITING

Beijing Friendship Hospital, Capital Medical University, Beijing

NOT_YET_RECRUITING

Chongqing University Three Gorges Hospital, Chongqing

NOT_YET_RECRUITING

The First People's Hospital of Foshan, Foshan

NOT_YET_RECRUITING

Fujian Medical University Union Hospital, Fuzhou

NOT_YET_RECRUITING

Affiliated Cancer Hospital of Guangzhou Medical University, Guangzhou

NOT_YET_RECRUITING

Nanfang Hospital Southern Medical University, Guangzhou

RECRUITING

Guangdong Provincial People's Hospital, Guanzhou

NOT_YET_RECRUITING

The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou

NOT_YET_RECRUITING

The First Affiliated Hospital of USTC Anhui Provincial Hospital, Hefei

NOT_YET_RECRUITING

The Affiliated Hospital of Inner Mongolia Hospital, Hohhot

NOT_YET_RECRUITING

The Affiliated Hospital of Qingdao University, Qingdao

NOT_YET_RECRUITING

Zhongshan Hospital Fudan University, Shanghai

NOT_YET_RECRUITING

Shenzhen People's Hospital, Shenzhen

NOT_YET_RECRUITING

Tongji Hospital Tongji College of HUST, Wuhan

NOT_YET_RECRUITING

The First Affiliated Hospital of Xiamen University, Xiamen

NOT_YET_RECRUITING

Zhongshan City People's Hospital, Zhongshan

All Listed Sponsors
lead

Guangdong Association of Clinical Trials

OTHER