Ulinastatin Improves and Prevents Cardiac Dysfunction Induced by Cardiopulmonary Bypass

NACompletedINTERVENTIONAL
Enrollment

236

Participants

Timeline

Start Date

September 16, 2022

Primary Completion Date

December 30, 2024

Study Completion Date

December 30, 2024

Conditions
Pharmacological Action
Interventions
DRUG

Ulinastatin

On the basis of conventional treatment, according to the instructions or previous research doses (general anesthesia and tracheal intubation, after cardiopulmonary bypass transfer starts): 10,000 U/kg Ulinastatin (National Medicine Approval No. H19990134, Guangdong Tianpu Biochemical Pharmaceutical Co., Ltd. Co., Ltd., Guangzhou, China) was dissolved in 50 ml of normal saline for 1 hour and pumped through the central vein.

OTHER

saline

On the basis of conventional treatment, 50 ml of normal saline for 1 hour and pumped through the central vein.

Trial Locations (1)

430030

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

All Listed Sponsors
lead

Qin Zhang

OTHER