NCT05530356View on ClinicalTrials.gov

Renal Hemodynamics, Energetics and Insulin Resistance: A Follow-up Study

Enrolling by invitationOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

September 30, 2022

Primary Completion Date

September 30, 2027

Study Completion Date

May 31, 2029

Conditions
Type 2 DiabetesDiabetes Type 2Diabetic NephropathiesNephropathyObesityAdolescent ObesityDiabetic Kidney Disease
Interventions
DRUG

Aminohippurate Sodium Inj 20%

Diagnostic aid/agent used to measure effective renal plasma flow (ERPF)

DRUG

Iohexol Inj 300 MG/ML

Diagnostic aid/agent used to measure glomerular filtration rate (GFR)

DRUG

Dextran 40

Diagnostic aid/agent used to measure glomerular size selectivity

PROCEDURE

Renal Biopsy

Minimally invasive outpatient procedure in interventional radiology to obtain renal tissue cores.

RADIATION

Positron Emission Tomography

Imaging study performed to study renal oxidative metabolism

Trial Locations (1)

80045

Children's Hospital Colorado, Aurora

All Listed Sponsors
lead

University of Colorado, Denver

OTHER