13
Participants
Start Date
April 22, 2022
Primary Completion Date
April 11, 2023
Study Completion Date
September 1, 2023
Same intervention for both groups: glycaemic index assessment of 3 biscuits recipes
Following International standards ISO 26642 guidelines, subjects (at fasting) will have their glycemia measured and after will consume a solution containing 50g of glucose and 100g of water. In the following 2 hours, glycemia and other blood parameters will be taken 6 times (at 15, 30, 45, 60, 90, and 120 minutes). This protocol is repeated twice within 3 months. After these 2 days, with the same methods, they will come to our clinic to test 3 different recipes of biscuits (characteristics are presented on request). Subjects and investigators are not blinded to these biscuits characteristics.
Crossover: Recipe 4 before recipe 5
"After the assessment of fasting parameters, subjects will consume recipe 4 (chocolate biscuits) and perform a 180 min curve with blood taken at 15, 30, 45, 60, 90, 120, and 180 minutes. In this case, both investigators and patients are blinded to the presence of an additional non-nutritive, non-toxic and without taste encapsulated bitter compound (artemisia absinthium), that could be present in recipe 4 or recipe 5. On the second day (with at least a week gap), patients will consume recipe 5. Questionnaires and a food diary will also be requested for subjects for lunch and dinner."
Crossover: Recipe 5 before recipe 4
Same as previous group, but starting with recipe 5
: Italy Pediatric Endocrine Service of AOU Maggiore della Carità of Novara; SCDU of Pediatrics, Department of Health Sciences, University of Eastern Piedmont, Novara
Polo AgriFood - Miac Scpa
UNKNOWN
Albertengo Panettoni
UNKNOWN
Azienda Ospedaliero Universitaria Maggiore della Carita
OTHER