Comparative Evaluation of Safety and Immune Activity of New Immunotherapeutic Agents for HDM Allergic Rhinitis Patients

PHASE1Enrolling by invitationINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

January 20, 2022

Primary Completion Date

December 21, 2024

Study Completion Date

June 15, 2025

Conditions
Mite AllergyRhinitis, AllergicHouse Dust Mite Rhinitis
Interventions
DRUG

House Dust Mite Extract, Dermatophagoides Farinae

"\[Group 1\] Group A receives 100 PAU at week 1 and 200 PAU at week 2 as the induction phase.~200 PAU is administered for 3 to 16 weeks as a maintenance phase.~Group B (placebo group) is the placebo arm of group A.~\[Group 2\] As the induction phase, group C received 100 PAU at week 1, 200 PAU at week 2, 300 PAU at week 3, and 400 PAU at week 4.~As the maintenance phase, 400 PAU is administered for 5 to 16 weeks.~Group D (placebo) is the placebo group in Group C.~\[Group 3\] As the induction phase, group E received 100 PAU at week 1, 200 PAU at week 2, 300 PAU at week 3, 400 PAU at week 4, 600 PAU at week 5, and 800 PAU at week 6.~As the maintenance phase, 800 PAU is administered from 7 to 16 weeks.~Group F (placebo) is the placebo arm of group E."

Trial Locations (1)

Unknown

Yonsei University Health System, Severance Hospital, Seoul

Sponsors

Lead Sponsor

All Listed Sponsors
lead

RAPHAS

INDUSTRY

NCT05525650 - Comparative Evaluation of Safety and Immune Activity of New Immunotherapeutic Agents for HDM Allergic Rhinitis Patients | Biotech Hunter | Biotech Hunter