Retro-active Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-identical Kidney Transplants

PHASE1RecruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

December 21, 2022

Primary Completion Date

September 30, 2026

Study Completion Date

September 30, 2026

Conditions
End Stage Kidney DiseaseImmunological ToleranceKidney Transplant Failure and RejectionChronic Kidney Diseases
Interventions
COMBINATION_PRODUCT

Conditioning and Stem cell infusion

Patients will undergo a conditioning with TLI and ATG, followed by infusion of hematopoietic stem cells from the same HLA-identical donor that provided the original kidney

Trial Locations (1)

90095

RECRUITING

UCLA, Los Angeles

All Listed Sponsors
lead

University of California, Los Angeles

OTHER