MYPP-trial: Myo-inositol Supplementation to Prevent Pregnancy Complications in Women With Polycystic Ovary Syndrome.

NAUnknownINTERVENTIONAL
Enrollment

464

Participants

Timeline

Start Date

June 21, 2019

Primary Completion Date

September 30, 2023

Study Completion Date

February 29, 2024

Conditions
Gestational Diabetes MellitusPreeclampsiaPreterm BirthPolycystic Ovary Syndrome
Interventions
DIETARY_SUPPLEMENT

Myo-inositol and routinely recommended folic acid

Participants randomly allocated to the intervention group will receive 4 grams myo-inositol added to their routinely recommended 0.4 mg folic acid supplement, divided over two daily sachets of sugary powder throughout pregnancy.

DIETARY_SUPPLEMENT

Routinely recommended folic acid

The control group will receive similar looking sachets of supplements containing only the standard dose of 0.4 mg folic acid without the added myo-inositol supplement as part of the current standard-of-care recommendation.

Trial Locations (1)

3015 GD

RECRUITING

Erasmus University Medical Center, Rotterdam

Sponsors
All Listed Sponsors
collaborator

ZonMw: The Netherlands Organisation for Health Research and Development

OTHER

lead

Erasmus Medical Center

OTHER