Doxycycline in Cutaneous Schwannoma (NF2)

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

19

Participants

Timeline

Start Date

September 19, 2022

Primary Completion Date

September 30, 2025

Study Completion Date

December 31, 2025

Conditions
Neurofibromatosis Type 2
Interventions
DRUG

Doxycycline Injection [Doxy]

Injections between 0.1 ml to 4 ml of 10mg/ml doxycycline hyclate will be administered to a maximum of three tumors per patient. The dose administered will be calculated based on tumor size, not to exceed the estimated volume of the tumor or a maximum of 4 ml. Injection of 1% lidocaine may be given pre-doxycycline to reduce injection pain.

Trial Locations (1)

02214

RECRUITING

Massachusetts Eye and Ear, Boston

All Listed Sponsors
lead

Massachusetts Eye and Ear Infirmary

OTHER