Deep, Multi-omics Phenotyping to Predict Response, Resistance and Recurrence to Adjuvant Atezolizumab Plus Bevacizumab in Resected Hepatocellular Carcinoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

February 28, 2023

Primary Completion Date

March 31, 2027

Study Completion Date

March 31, 2027

Conditions
Hepatocellular Carcinoma
Interventions
PROCEDURE

Surgical Resection

Resection of Primary Hepatocellular Cancer Tumour.

DRUG

Adjuvant Atezolizumab-Bevacizumab Therapy

Patient receives adjuvant Atezolizumab plus Bevacizumab every 3-weekly for two years following resection of hepatocellular carcinoma tumour.

Trial Locations (6)

119074

RECRUITING

National University Hospital Singapore, Singapore

169610

RECRUITING

National Cancer Centre Singapore, Singapore

169856

RECRUITING

Singapore General Hospital, Singapore

308433

ACTIVE_NOT_RECRUITING

Tan Tock Seng Hospital, Singapore

529889

RECRUITING

Changi General Hospital, Singapore

544886

RECRUITING

Sengkang General Hospital, Singapore

All Listed Sponsors
collaborator

Singapore General Hospital

OTHER

collaborator

National University Hospital, Singapore

OTHER

collaborator

Changi General Hospital

OTHER

collaborator

Sengkang General Hospital

OTHER

collaborator

Tan Tock Seng Hospital

OTHER

collaborator

Singapore Clinical Research Institute

OTHER

collaborator

Genome Institute of Singapore

OTHER

collaborator

Institute of Molecular and Cell Biology of Singapore

UNKNOWN

collaborator

Cancer Science Institute of Singapore

UNKNOWN

collaborator

Duke-NUS Graduate Medical School

OTHER

collaborator

Singapore Phenome Centre

UNKNOWN

collaborator

Nanyang Technological University

OTHER

collaborator

NMRC OF-LCG (OFLCG21Jun-0016)

UNKNOWN

lead

National Cancer Centre, Singapore

OTHER

NCT05516628 - Deep, Multi-omics Phenotyping to Predict Response, Resistance and Recurrence to Adjuvant Atezolizumab Plus Bevacizumab in Resected Hepatocellular Carcinoma | Biotech Hunter | Biotech Hunter