Beneficial Effects of Daytime Light Exposure and Physical Activity on the Human Circadian Clock and Sleep

NACompletedINTERVENTIONAL
Enrollment

51

Participants

Timeline

Start Date

April 27, 2023

Primary Completion Date

September 12, 2025

Study Completion Date

September 12, 2025

Conditions
Circadian System
Interventions
OTHER

LE protocol 1: exposure to artificial light

Participants stay in the lab with light mimicking usual office lighting. On days 8, 15, and 22, participants start the experimental protocol 5 hours before HBT: questionnaires, behavioural responsiveness (assessed by PVT), saliva samples for melatonin measurements (until HBT and two more following awakening the next day). Participants will go to bed at HBT and get up 8h later in the morning. Their sleep will be assessed with PSG recordings.

OTHER

LE protocol 2: natural daylight

Participants spend the same time outdoors in natural daylight. On days 8, 15, and 22, participants start the experimental protocol 5 hours before HBT: questionnaires, behavioural responsiveness (assessed by PVT), saliva samples for melatonin measurements (until HBT and two more following awakening the next day). Participants will go to bed at HBT and get up 8h later in the morning. Their sleep will be assessed with PSG recordings.

OTHER

LE protocol 3: natural daylight with reduced short-wavelength proportions

Participants spend the same time outdoors in natural daylight wearing tinted glasses that filter out short-wavelength light proportions. On days 8, 15, and 22, participants start the experimental protocol 5 hours before HBT: questionnaires, behavioural responsiveness (assessed by PVT), saliva samples for melatonin measurements (until HBT and two more following awakening the next day). Participants will go to bed at HBT and get up 8h later in the morning. Their sleep will be assessed with PSG recordings.

Trial Locations (1)

4002

Centre for Chronobiology, Psychiatric Hospital of the University of Basel, Basel

All Listed Sponsors
collaborator

Swiss National Science Foundation

OTHER

lead

University Hospital, Basel, Switzerland

OTHER

NCT05513547 - Beneficial Effects of Daytime Light Exposure and Physical Activity on the Human Circadian Clock and Sleep | Biotech Hunter | Biotech Hunter