Phase II Dutasteride in Combination With CAB vs CAB in SDC

PHASE2RecruitingINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

September 27, 2022

Primary Completion Date

September 30, 2025

Study Completion Date

September 30, 2027

Conditions
Salivary Duct Carcinoma
Interventions
DRUG

Goserelin 10.8 mg

Goserelin injection (10.8 mg) once per 3 months until progressive disease, intolerable toxicity, or investigator and/or patient decision to withdraw.

DRUG

Bicalutamide 50 mg

Bicalutamide tablets (50 mg) once daily until progressive disease, intolerable toxicity, or investigator and/or patient decision to withdraw.

DRUG

Dutasteride 0.5 mg

Dutasteride capsules (0.5 mg) once daily until progressive disease, intolerable toxicity, or investigator and/or patient decision to withdraw.

Trial Locations (1)

6500HB

RECRUITING

Radboudumc, Nijmegen

All Listed Sponsors
collaborator

ZonMw: The Netherlands Organisation for Health Research and Development

OTHER

lead

Radboud University Medical Center

OTHER