Dasatinib and Quercetin to Treat Fibrotic Non-alcoholic Fatty Liver Disease

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

March 1, 2023

Primary Completion Date

October 31, 2024

Study Completion Date

October 31, 2025

Conditions
NAFLDNASH With FibrosisLiver Fibrosis
Interventions
DRUG

Dasatinib 100 MG + Quercetin (1000 MG)

The intervention group will receive intermittent orally administered dasatinib (100 mg/day) plus quercetin (1000 mg/day) on three consecutive days for three consecutive weeks followed by a four-week medication free period. This cycle will be repeated three times.

OTHER

Placebo

The placebo group will receive intermittent orally administered placebo tablets on three consecutive days for three consecutive weeks followed by a four-week medication free period. This cycle will be repeated three times.

Trial Locations (1)

Unknown

RECRUITING

Amsterdam UMC location AMC, Amsterdam

All Listed Sponsors
lead

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

OTHER