100
Participants
Start Date
August 12, 2022
Primary Completion Date
June 30, 2024
Study Completion Date
December 30, 2026
Rituximab
Young patients (\< 65 years of age) were treated with R-BAP for 6 cycles (efficacy was assessed every 2 cycles, and adverse events were recorded), together with oral ibrutinib, followed by oral ibrutinib for 1 year after chemotherapy (efficacy was assessed every 3 months). Elderly patients (≥65 years of age) received 4 cycles of R-BAP (efficacy assessed every 2 cycles, and adverse reactions recorded), followed by 4 cycles of rituximab consolidation (efficacy assessed every 2 cycles) and 1 year of oral zanubrutinib (efficacy assessed every 3 months).
RECRUITING
Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou
Zhengzhou University
OTHER