Phase II Study of PARP Inhibitor Olaparib and IV Ascorbate in Castration Resistant Prostate Cancer

PHASE2TerminatedINTERVENTIONAL
Enrollment

4

Participants

Timeline

Start Date

June 30, 2023

Primary Completion Date

October 14, 2024

Study Completion Date

October 14, 2024

Conditions
Prostate CancerCastration-resistant Prostate Cancer
Interventions
DRUG

Olaparib

Olaparib 300mg by mouth twice daily

DIETARY_SUPPLEMENT

Vitamin C

Ascorbic acid 1g/kg administered intravenously twice weekly

Trial Locations (2)

20016

Sibley Memorial Hospital, Washington D.C.

21287

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

collaborator

McGuff Pharmaceuticals, Inc.

INDUSTRY

collaborator

The Marcus Foundation

OTHER

lead

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

OTHER