A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES)

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

700

Participants

Timeline

Start Date

August 26, 2022

Primary Completion Date

December 31, 2026

Study Completion Date

January 31, 2027

Conditions
NASHCirrhosis, Liver
Interventions
DRUG

Resmetirom

Randomized 80 mg

DRUG

Placebo

randomized matching placebo

Trial Locations (55)

19031

Regional Gastroenterology Associates of Lancaster, Flourtown

21202

Mercy Medical Center, Baltimore

23236

GI Select Health Research, Richmond

23249

Hunter Holmes McGuire VA Medical Center, Richmond

28557

Lucas Research, Morehead City

30060

Gastrointestinal Specialists of Georgia, Marietta

30607

Summit Clinical Research, Athens

32086

St Johns Center for Clinical Research, Saint Augustine

32159

Ocala GI Research DBA Lake Center for Clinical Research, Lady Lake

32216

Jacksonville Center for Clinical Research, Jacksonville

33134

Hi Tech and Global Research, Coral Gables

33157

Sanchez Clinical Research, Miami

33189

Top Medical Research Inc, Cutler Bay

33542

Florida Medical Clinic, Zephyrhills

33614

International Center for Research, Tampa

33912

Covenant Research - Fort Myers, Fort Myers

34238

Florida Research Institute, Lakewood Rch

34240

Covenant Research, Sarasota

34452

Nature Coast Clinical Research - Inverness, Inverness

34471

Ocala GI Research, Ocala

35249

University of Alabama at Birmingham (UAB), Birmingham

37040

Premier Medical Group, Clarksville

38018

Gastro One, Cordova

57701

Rapid City Medical Center, Rapid City

64131

Kansas City Research Institute, Kansas City

71105

Louisiana Research Center, Shreveport

71220

Delta Research Partners - Bastrop, Bastrop

72117

Arkansas Gastroenterology, North Little Rock

75203

The Liver Institute at Methodist Dallas Medical Center, Dallas

75234

Liver Center of Texas, Dallas

76710

Impact Research Institute, Waco

76712

Digestive Health Research of Central Texas, Waco

77079

Houston Research Institute, Houston

78229

Pinnacle Clinical Research - San Antonio, San Antonio

78520

South Texas Research Institute - Brownsville, Brownsville

78539

South Texas Research Institute - Edinburg, Edinburg

78626

Pinnacle Clinical Research - Georgetown, Georgetown

78757

Pinnacle Clinical Research - Austin, Austin

80113

South Denver Gastroenterology, Englewood

85224

Arizona Liver Health - Chandler, Chandler

85381

Arizona Liver Health - Peoria, Peoria

85712

Adobe Clinical Research, Tucson

Arizona Liver Health - Tucson, Tucson

90033

Keck School of Medicine of USC, Los Angeles

91105

California Liver Research Institute, Pasadena

92037

Univ. of California San Diego School of Medicine, La Jolla

92118

Southern California Research Center, Coronado

93701

University of California, San Francisco-Fresno, Fresno

98105

Liver Institute Northwest, Seattle

666006

Kansas Medical Clinic - Gastroenterology, Topeka

72205-6414

Arkansas Diagnostic Center/Liver Wellness Center, Little Rock

07871

Premier Health Research, Sparta

76012-3216

Texas Clinical Research Institute, Arlington

00909

Latin Clinical Trials Center, San Juan

00927

FDI Clinical Research (Fundacion de Investigacion de Diego), San Juan

Sponsors
All Listed Sponsors
lead

Madrigal Pharmaceuticals, Inc.

INDUSTRY