The Franciscus Obesity NASH Study

Active, not recruitingOBSERVATIONAL
Enrollment

300

Participants

Timeline

Start Date

September 1, 2022

Primary Completion Date

September 1, 2023

Study Completion Date

September 1, 2029

Conditions
NAFLDNASH - Nonalcoholic SteatohepatitisObesity, Morbid
Interventions
DIAGNOSTIC_TEST

NASH screening

Evaluate liver steatosis and elasticity using transient elastography in the FONS group

DIAGNOSTIC_TEST

Cardiac dysfunction screening

Evaluate cardiac dysfunction in 60 patients from the FONS group with transthoracic echocardiography

DIAGNOSTIC_TEST

Liver biopsy

For participants from the FONS group with an elevated liver fibrosis measurement (≥F2) with TE, a laparoscopic liver biopsy will be performed during the bariatric procedure.

Trial Locations (1)

3045PM

Franciscus Gasthuis, Rotterdam

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Amsterdam UMC

OTHER

collaborator

Erasmus Medical Center

OTHER

collaborator

Leiden University Medical Center

OTHER

lead

Franciscus Gasthuis

OTHER