NCT05497804 - Combination Treatment Therapy Approaches for the Treatment of High-Risk Multiple Myeloma, REACH Trial | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

September 22, 2022

Primary Completion Date

November 20, 2027

Study Completion Date

November 20, 2028

Conditions

ISS Stage III Plasma Cell MyelomaMultiple Myeloma

Interventions

PROCEDURE

Bone Marrow Aspiration and Biopsy

Undergo bone marrow aspiration and biopsy

DRUG

Carfilzomib

Given IV

PROCEDURE

Computed Tomography

Undergo CT or PET/CT

BIOLOGICAL

Daratumumab

Given SC

DRUG

Dexamethasone

Given IV/PO

DRUG

Lenalidomide

Given PO

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI

PROCEDURE

Positron Emission Tomography

Undergo PET/CT

PROCEDURE

Multigated Acquisition Scan

Undergo MUGA scan

PROCEDURE

Biospecimen Collection

Undergo blood sample collection

PROCEDURE

Echocardiography

Undergo ECHO

PROCEDURE

Chest Radiography

Undergo chest x-ray

Trial Locations (3)

55905

RECRUITING

Mayo Clinic in Rochester, Rochester

85259

RECRUITING

Mayo Clinic in Arizona, Scottsdale

32224-9980

RECRUITING

Mayo Clinic, Jacksonville