A Exploratory Study of Vγ2Vδ2 T Lymphocyte-based Immunotherapy for MDR-TB

PHASE4RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

August 3, 2022

Primary Completion Date

August 3, 2025

Study Completion Date

August 3, 2027

Conditions
MDR-TBImmunotherapy
Interventions
DRUG

Vγ2Vδ2 T lymphocyte-based immunotherapy

Intravenous injection of zoledronic acid, followed by a subcutaneous injection recombinant human interleukin. Zoledronic acid was administered 3 times and recombinant human interleukin was administered 10 times for a total of 6 months.

DRUG

Treatment regimens for MDR-TB

Treatment regimens was based on the principles of the WHO guidelines for the treatment of drug-resistant tuberculosis.

Trial Locations (2)

200433

RECRUITING

Shanghai Pulmonary Hospital, Shanghai, China, Shanghai

Unknown

RECRUITING

Shanghai Pulmonary Hospital, Shanghai

All Listed Sponsors
collaborator

Shanghai Public Health Clinical Center

OTHER_GOV

collaborator

Huashan Hospital

OTHER

collaborator

No.85 Hospital, Changning, Shanghai, China

OTHER

lead

Shanghai Pulmonary Hospital, Shanghai, China

OTHER