Functional Connectivity Alterations in Suicidal Patients Among Opioid Users

NARecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

January 4, 2022

Primary Completion Date

February 28, 2027

Study Completion Date

March 31, 2027

Conditions
Substance AbuseSuicideDepression
Interventions
DEVICE

Repetitive Transcranial Magnetic Stimulation (rTMS)

5 Sessions of rTMS - brief single pulse TMS or short TMS pulse bursts consisting of 2-5 pulses delivered per second at a standard intensity. If a brief single pulse TMS is applied, a standard single pulse TMS procedure will be used - This procedure consists of 10 trains of 180 seconds duration and each train will be separated by at least 30 seconds. If short TMS pulse bursts are applied, a standard theta-burst TMS procedure will be used - This procedure consists of TMS triplets (i.e., 3 pulses) that repeat for 10 trains of a total duration of 40-190 seconds and these bursts will be separated by at least 6 seconds and each train will be separated by at least 30 seconds

DEVICE

sham rTMS

5 sessions of sham rTMS

Trial Locations (1)

77035

RECRUITING

The Menninger Clinic, Houston

All Listed Sponsors
collaborator

American Foundation for Suicide Prevention

OTHER

collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

Baylor College of Medicine

OTHER