A Research Study to Look Into How Well Semaglutide Medicine Works at Different Doses in People With Type 2 Diabetes and Overweight

PHASE2CompletedINTERVENTIONAL
Enrollment

245

Participants

Timeline

Start Date

August 8, 2022

Primary Completion Date

October 12, 2023

Study Completion Date

December 13, 2023

Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG

Semaglutide

Semaglutide s.c. injection once-weekly for 40 weeks. Dose gradually increased over 24 weeks, followed by a 16 week maintenance period.

DRUG

Placebo

Semaglutide placebo s.c. injection once-weekly for 40 weeks. Dose gradually increased over 24 weeks, followed by a 16 week maintenance period.

Trial Locations (72)

1032

Szent Margit Rendelőintézet Nonprofit Kft., Budapest

1089

ClinDiab Egészségügyi Szolgáltató és Kereskedelmi Kft., Budapest

1106

Bajcsy-Zsilinszky Kórház, Budapest

1134

MH Egészségügyi Központ, Budapest

2900

Selye János Kórház és Rendelőintézet, Komárom

11768

Northport VA Med Ctr Northport, Northport

12203

Albany Medical College - Endo, Albany

12553

Mid Hudson Med Res-New Windsor, New Windsor

14224

Southgate Medical Group, LLP, West Seneca

19114

Clinical Research of Philadelphia, Philadelphia

20745

MD Medical Research, Oxon Hill

20782

MedStar Community Clin Res Ctr, Hyattsville

20852

Endo And Metab Cons, Rockville

27514

UNC Eastowne Clinical Research Unit, Chapel Hill

28401

Accellacare, Wilmington

32204

Northeast Res Inst. Inc., Jacksonville

32801

Clinical Neuroscience Solution, Orlando

33014

San Marcus Res Clin Miami Lakes, Miami Lakes

35294

Univ of Alabama Birmingham, Birmingham

University of Alabama Birmingham, Birmingham

37660

Holston Medical Group, Kingsport

38119

Clinical Neuroscience Solutions, Memphis

40503

The Research Group of Lexington LLC, Lexington

43537

Advanced Med Res Maumee, Maumee

45439

Providence Health Partners Ctr, Dayton

48098

Arcturus Healthcare, PLC, Troy

51501

West Broadway Clinic, Council Bluffs

53144

Clinical Inv Spec, Inc.Kenosha, Kenosha

58104

Lillestol Research LLC, Fargo

60607

Cedar-Crosse Research Center, Chicago

63303

StudyMetrix Research LLC, City of Saint Peters

66606

Cotton O'Neil Clin Research Ctr, Topeka

75230

Velocity Clinical Res-Dallas, Dallas

78231

Consano Clinical Research, LLC, Shavano Park

79106

Amarillo Med Spec LLP, Amarillo

83646

Solaris Clinical Research, Meridian

90057

Velocity Clin Res Wstlke, Los Angeles

90247

Velocity Clin Res Gardena, Gardena

90255

National Research Institute_Huntington Park, Huntington Park

92111

San Diego Family Care_San Diego, San Diego

92118

Southern California Res Ctr, Coronado

92220

Velocity Clinical Res-Banning, Banning

93534

First Valley Med Grp Lancaster, Lancaster

94401

Mills-Peninsula Hlth Services, San Mateo

94598

Diablo Clinical Research, Inc., Walnut Creek

97504

Velocity Clinical Res Medford, Medford

97527

Velocity Clin Res Grants Pass, Grants Pass

02115-5804

Brigham & Women's Hospital, Boston

08611

Premier Research Inc., Trenton

75390-9302

UT Southwestern Med Cntr, Dallas

GR-12462

University Hospital of Athens ATTIKON, Haidari-Athens

115 25

Iatriko Psychicou Private Clinic, Athens

GR-11527

Gen Hospital of Athens Laiko,1st Dpt. of Propaedeutic Inter, Athens

GR-11528

Alexandra General Hospital, Therapeutic Clinic, Athens

GR-15125

Iatriko Athinon (Athens Medical Canter), Athens

GR-17562

Iatriko Athinon 'Palaiou Falirou', Athens

GR 54642

'Ippokrateio' General Hospital of Thessaloniki, Thessaloniki

GR-54635

General Hospital of Thessaloniki 'G. Gennimatas, Thessaloniki

GR-54643

EUROMEDICA Gen Clinic The/ki, Endocrin,Metabolism,Diabetes, Thessaloniki

GR-57001

"Thermi Private Hosital", Thessaloniki

GR-57010

"General Hospital of Thessaloniki G.Papanikolaou", Thessaloniki

H-6725

Szegedi Tudomanyegyetem St Györgyi Albert Klinikai Központ, Szeged

H-9700

Markusovszky Egyetemi Oktatókórház, Szombathely

00-465

NBR Polska, Warsaw

15-435

NZOZ Specjalistyczny Osrodek Internistyczno-Diabetologiczny Małgorzata Arciszewska, Bialystok

15-879

NZOZ Vita-Diabetica Malgorzata Buraczyk, Bialystok

40-648

Pro Familia Altera Sp. z o.o., Katowice

28-200

Ko-Med Centra Kliniczne Staszow, Staszów

Velocity Nova Sp. z o.o., Staszów

00-710

NBR Polska Tomasz Klodawski, Warsaw

96-100

Clinmedica Research sp. z o.o., Skierniewice

00674

Manati Ctr For Clin Research, Manatí

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Novo Nordisk A/S

INDUSTRY

NCT05486065 - A Research Study to Look Into How Well Semaglutide Medicine Works at Different Doses in People With Type 2 Diabetes and Overweight | Biotech Hunter | Biotech Hunter