23
Participants
Start Date
July 16, 2024
Primary Completion Date
June 30, 2028
Study Completion Date
September 30, 2028
Pembrolizumab
200 mg fixed dose, IV, every 3 weeks (Q3W), on Days 1 of Cycles 1-4
Paclitaxel
80 mg/m2, IV, weekly, on Days 1, 8, 15 of Cycles 1-4
Carboplatin
Area under the curve (AUC 1.5), intravenously (IV), weekly, on Days 1, 8, 15 of Cycles 1-4
Olaparib
300 mg BID (twice daily) orally
Definitive Surgery
Each subject will undergo definitive surgery 3-6 weeks after conclusion of the last cycle of the neoadjuvant treatment.
RECRUITING
Gifu University Hospital, Gifu
RECRUITING
Okayama University Hospital, Okayama
RECRUITING
St. Luke's International Hospital, Tokyo
Merck Sharp & Dohme LLC
INDUSTRY
Okayama University
OTHER