Lactobacillus Reuteri Strain Combination in Children Treated With PPI

NARecruitingINTERVENTIONAL
Enrollment

172

Participants

Timeline

Start Date

March 4, 2020

Primary Completion Date

June 30, 2025

Study Completion Date

December 31, 2025

Conditions
Gastric LesionProton Pump Inhibitor Adverse ReactionProbiotic
Interventions
DIETARY_SUPPLEMENT

Gastrus

"Gastrus consisted of a mixture of two human strains of L. Reuteri DSM 17938 and ATCC PTA 6475.~Gastrus will be administered for all the duration of PPI administration (8 weeks) plus two weeks after its discontinuation. A final evaluation will be performed 4 weeks after the discontinuation of both Gastrus."

OTHER

Placebo

placebo has an identical preparation to Gastrus

Trial Locations (1)

70100

RECRUITING

Fernanda, Bari

All Listed Sponsors
lead

University of Bari

OTHER