Evaluating Novel Therapies in ctDNA Positive GI Cancers

PHASE3RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

March 29, 2023

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2028

Conditions
Colon AdenocarcinomaRectal AdenocarcinomaGastric AdenocarcinomaPancreatic AdenocarcinomaHepatocellular CarcinomaAdenocarcinoma of Biliary TractGallbladder Adenocarcinoma
Interventions
DRUG

Atezolizumab

Atezolizumab is a monoclonal antibody that belongs to a class of drugs that bind to either the programmed death-receptor 1 (PD-1) or the PD-ligand 1 (PD-L1), blocking the PD-1/PD-L1 pathway,

DRUG

Bevacizumab

Bevacizumab is a tumor-starving (anti-angiogenic) therapy. Avastin is designed to block a protein called vascular endothelial growth factor, or VEGF.

Trial Locations (3)

20007

RECRUITING

Georgetown Lombardi Comprehensive Cancer Center, Washington D.C.

20010

RECRUITING

Medstar Washington Hospital Center, Washington D.C.

07601

RECRUITING

John Theurer Cancer Center at Hackensack University Medical Center, Hackensack

Sponsors
All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

collaborator

Natera, Inc.

INDUSTRY

lead

Georgetown University

OTHER