A Study of Detergents in the Pathogenesis of Eosinophilic Esophagitis

NAActive, not recruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

September 12, 2022

Primary Completion Date

July 31, 2025

Study Completion Date

July 31, 2025

Conditions
Eosinophilic Esophagitis
Interventions
DIAGNOSTIC_TEST

Esophageal String Test (EST)

Non-invasive, FDA-registered sampling method to evaluate eosinophilic inflammation in the esophagus. The EST is performed by having an individual swallow a capsule attached to a string which captures secretions from the esophagus. The end of the string is taped to the cheek and the capsule is swallowed with water. After 1 hour, the EST will be removed, and the string will be processed for laboratory analysis.

OTHER

Colgate

2 grams of toothpaste (pea sized amount) for 2 minutes

DIAGNOSTIC_TEST

High Resolution Esophageal Manometry (HREM)

Thin flexible tube with sensors placed in the nose and swallowed for esophagus placement to conduct reading regarding the lining of the esophagus taken for approximately 10 minutes

Trial Locations (1)

85259

Mayo Clinic Arizona, Scottsdale

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Mayo Clinic

OTHER