An Exploratory Study to Evaluate Immune Determinants of the Response to Adoptive Cell Therapy (ACT) in Solid and Hematologic Tumors

NARecruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

June 8, 2022

Primary Completion Date

July 1, 2027

Study Completion Date

July 1, 2027

Conditions
Solid Tumor, AdultSolid Tumor, ChildhoodHematologic Cancer
Interventions
PROCEDURE

Tumor biopsy

3 biopsies will be collected: at baseline, at day+15 and optionally at relapse

PROCEDURE

Blood sample

7 blood samples (25ml) will be taken: at day-7 before treatment start, at day0, at day+3, day+7, day+15, month+3 and at relapse

PROCEDURE

Bone marrow sample

If a bone marrow biopsy or aspiration is performed as part of routine care, 1 mL of bone marrow aspiration or one more biopsy will be sampled

Trial Locations (1)

94805

RECRUITING

Gustave Roussy Cancer Campus Grand Paris, Villejuif

All Listed Sponsors
lead

Gustave Roussy, Cancer Campus, Grand Paris

OTHER