120
Participants
Start Date
April 17, 2023
Primary Completion Date
July 31, 2026
Study Completion Date
January 31, 2027
Neurocognitive (Thinking) Testing
"Intelligence: WASI-II 20 min; Sustained Attention:~Conners Continuous Performance Test 3rd ED. 15 min; Memory: California Verbal Learning Test 2nd Ed. 20 min; Visual Selective Reminding 7 min; Processing Speed:Coding/Digit Symbol 3 min; Grooved Pegboard 5 min; Executive Function: Trail Making Test 5 min; Verbal Fluency Test 3 min; Digit Span 5 min; Visuospatial: Rey Complex Figure 10 min; Functional Behavior: CCSS Neurocognitive Questionnaire 5 min."
CNS Vital Signs (Thinking) Testing
Attention: Continuous Performance Task 5 mins Processing Speed: Symbol Digit Test 4 mins Executive Function: Shifting Attention 3 min and Stroop Test 5 mins
Health Questionnaires, Sleep Surveys & Sleep Diary
The participant will be asked to complete the sleep surveys and sleep diary, FACIT fatigue, and CSALTS Pain Survey These questionnaires will take about 29 minutes to complete. The sleep diary is completed at the time the participant wears the sleep device.
Echocardiography/EKG
All echocardiograms will be performed using a General Electric VIVID-7. The LV volume, mass and EF will be calculated using the recommendations of the American Society of Echocardiography
Pulmonary Function
PFTs will include spirometry, lung volume measurements by body plethysmography and single breath carbon monoxide-diffusion capacity (DLCO).
Remote Polysomnography
The Sleep Profiler PSG2/WatchPat device will be used to assess nighttime sleep disorders.
Physical Function
This is a test of how your heart and lungs respond to exercise.
RECRUITING
St. Jude Children's Research Hospital, Memphis
St. Jude Children's Research Hospital
OTHER