Characterizing Sleep Among Long-term Survivors of Childhood Cancer

RecruitingOBSERVATIONAL
Enrollment

120

Participants

Timeline

Start Date

April 17, 2023

Primary Completion Date

July 31, 2026

Study Completion Date

January 31, 2027

Conditions
ALL, AdultCNS TumorSolid Tumor
Interventions
OTHER

Neurocognitive (Thinking) Testing

"Intelligence: WASI-II 20 min; Sustained Attention:~Conners Continuous Performance Test 3rd ED. 15 min; Memory: California Verbal Learning Test 2nd Ed. 20 min; Visual Selective Reminding 7 min; Processing Speed:Coding/Digit Symbol 3 min; Grooved Pegboard 5 min; Executive Function: Trail Making Test 5 min; Verbal Fluency Test 3 min; Digit Span 5 min; Visuospatial: Rey Complex Figure 10 min; Functional Behavior: CCSS Neurocognitive Questionnaire 5 min."

DIAGNOSTIC_TEST

CNS Vital Signs (Thinking) Testing

Attention: Continuous Performance Task 5 mins Processing Speed: Symbol Digit Test 4 mins Executive Function: Shifting Attention 3 min and Stroop Test 5 mins

OTHER

Health Questionnaires, Sleep Surveys & Sleep Diary

The participant will be asked to complete the sleep surveys and sleep diary, FACIT fatigue, and CSALTS Pain Survey These questionnaires will take about 29 minutes to complete. The sleep diary is completed at the time the participant wears the sleep device.

DIAGNOSTIC_TEST

Echocardiography/EKG

All echocardiograms will be performed using a General Electric VIVID-7. The LV volume, mass and EF will be calculated using the recommendations of the American Society of Echocardiography

DIAGNOSTIC_TEST

Pulmonary Function

PFTs will include spirometry, lung volume measurements by body plethysmography and single breath carbon monoxide-diffusion capacity (DLCO).

DEVICE

Remote Polysomnography

The Sleep Profiler PSG2/WatchPat device will be used to assess nighttime sleep disorders.

DIAGNOSTIC_TEST

Physical Function

This is a test of how your heart and lungs respond to exercise.

Trial Locations (1)

38105

RECRUITING

St. Jude Children's Research Hospital, Memphis

All Listed Sponsors
lead

St. Jude Children's Research Hospital

OTHER