A Study to Examine the Effect of Daridorexant on the Way the Body Absorbs, Distributes, and Gets Rid of Midazolam and Warfarin in Healthy Male Subjects

PHASE1CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

August 23, 2022

Primary Completion Date

September 23, 2022

Study Completion Date

October 6, 2022

Conditions
Healthy
Interventions
DRUG

Midazolam

Subjects will receive a single oral dose of 2 mg midazolam (Treatment A, B, and C).

DRUG

Warfarin

Subjects will receive a single oral dose of 25 mg warfarin (Treatment A and B).

DRUG

Daridorexant

Subjects will receive an o.d. oral dose of 50 mg daridorexant from Day 1 to Day 7 of Treatment B and a single oral dose of 50 mg daridorexant on Day 1 of Treatment C.

Trial Locations (1)

89231

Nuvisan GmbH, Neu-Ulm

Sponsors
All Listed Sponsors
lead

Idorsia Pharmaceuticals Ltd.

INDUSTRY