Dose Escalation and Expansion Study of WTX-124 as Monotherapy and in Combination With Pembrolizumab (Pembro) in Patients With Selected Advanced or Metastatic Solid Tumors

PHASE1RecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

May 20, 2022

Primary Completion Date

July 1, 2026

Study Completion Date

July 31, 2026

Conditions
Metastatic Solid TumorAdvanced Solid Tumor
Interventions
DRUG

WTX-124

Investigation Product Monotherapy

DRUG

pembrolizumab

Investigation Product in combination with approved therapy

Trial Locations (14)

10532

TERMINATED

Westchester Medical Center, Hawthorne

14203

RECRUITING

Roswell Park Comprehensive Cancer Care, Buffalo

30322

RECRUITING

Emory Winship Cancer Institute, Atlanta

33612

RECRUITING

Moffitt Cancer Center, Tampa

46202

RECRUITING

Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis

55369

RECRUITING

Minnesota Oncology Hematology, P.A., Maple Grove

60611

RECRUITING

Northwestern University, Chicago

77054

RECRUITING

NEXT Oncology, Houston

78229

RECRUITING

NEXT Oncology, San Antonio

85258

RECRUITING

HonorHealth, Scottsdale

97213

RECRUITING

Providence Cancer Institute Franz Clinic, Portland

07601

RECRUITING

Hackensack University Medical Center, Hackensack

78705-1165

RECRUITING

Texas Oncology - Austin Midtown, Austin

75390-8852

RECRUITING

University of Texas Southwestern Medical Center, Dallas

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

Werewolf Therapeutics, Inc.

INDUSTRY