Genetically Modified Cells (KIND T Cells) for the Treatment of HLA-A*0201-Positive Patients With H3.3K27M-Mutated Glioma

PHASE1RecruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

July 20, 2023

Primary Completion Date

August 31, 2029

Study Completion Date

August 31, 2029

Conditions
Diffuse Midline Glioma, H3 K27M-Mutant
Interventions
DRUG

Cyclophosphamide

Given IV

DRUG

Fludarabine

Given IV

BIOLOGICAL

Autologous Anti-H3.3K27M TCR-expressing T-cells

Given IV

Trial Locations (1)

94143

RECRUITING

University of California, San Francisco, San Francisco

All Listed Sponsors
collaborator

The V Foundation

OTHER

collaborator

Parker Institute for Cancer Immunotherapy

OTHER

collaborator

Alliance for Cancer Gene Therapy

OTHER

lead

University of California, San Francisco

OTHER