A Phase 2a Study to Investigate REM0046127 in Mild to Moderate Alzheimer's Disease

PHASE2TerminatedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

June 7, 2022

Primary Completion Date

June 4, 2024

Study Completion Date

June 4, 2024

Conditions
Alzheimer Disease
Interventions
DRUG

REM0046127 High Dose

"Each subject will start with a 14-day placebo run-in period, followed by a 28-day treatment period and 7-day follow-up period.~REM0046127 high dose: 1400mg (700mg bid) oral suspension per day for 28 days"

DRUG

REM0046127 Low Dose

"Each subject will start with a 14-day placebo run-in period, followed by a 28-day treatment period and 7-day follow-up period.~REM0046127 low dose: 350mg (175mg bid) oral suspension per day for 28 days"

DRUG

Placebo

"Each subject will start with a 14-day placebo run-in period, followed by a 28-day treatment period and 7-day follow-up period.~Placebo: placebo oral suspension bid for 28 days and during the 14-days run-in phase"

Trial Locations (3)

1081

BRC Amsterdam, Amsterdam

41013

FISEVI Hospital Universitario Virgen del Rocio, Seville

08029

Fundacion ACE, Barcelona

Sponsors

Lead Sponsor

All Listed Sponsors
lead

reMYND

INDUSTRY