Dual-targeting VEGFR1 and PD-L1 CAR-T for Cancers Patients With Pleural or Peritoneal Metastases

PHASE1RecruitingINTERVENTIONAL
Enrollment

58

Participants

Timeline

Start Date

November 28, 2023

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Malignant Peritoneal EffusionMalignant AscitesSerous Cavity Metastatises
Interventions
BIOLOGICAL

Dual-targeting VEGFR1 and PD-L1 CAR-T cells

"In the dose escalation part, the dose levels will be escalated following a traditional escalation scheme for 3+3 design.~In the dose expansion part, patients will be assigned to different groups based on pleural or peritoneal metastases condition."

Trial Locations (1)

610041

RECRUITING

West China Hospital, Sichuan University, Chengdu

All Listed Sponsors
lead

Sichuan University

OTHER