NCT05472779View on ClinicalTrials.gov

Periurethral vs Intravaginal Estrogen for Prevention of Recurrent Urinary Tract Infections

PHASE2CompletedINTERVENTIONAL
Enrollment

114

Participants

Timeline

Start Date

January 3, 2023

Primary Completion Date

June 15, 2025

Study Completion Date

June 25, 2025

Conditions
Recurrent Urinary Tract Infection
Interventions
DRUG

Periurethral application of estradiol cream

The experimental group will apply estradiol cream in a different location (periurethral) and at a smaller dose (0.5 gram) compared to the control group.

DRUG

Intravaginal application of estradiol cream

The control group will apply 1 gram estradiol cream intravaginally using an applicator.

Trial Locations (4)

15213

University of Pittsburgh Medical Center-Magee Womens Hospital, Pittsburgh

15237

UPMC Passavant-McCandless, Pittsburgh

16066

UPMC Lemieux Sports Complex, Cranberry Township

16550

UPMC Hamot, Erie

All Listed Sponsors
lead

Stephanie Wang Zuo

OTHER