A Study to Evaluate the Efficacy and Safety of AK111 in Subjects With Active Ankylosing Spondylitis

PHASE2CompletedINTERVENTIONAL
Enrollment

125

Participants

Timeline

Start Date

June 2, 2021

Primary Completion Date

April 25, 2022

Study Completion Date

May 19, 2022

Conditions
Ankylosing Spondylitis
Interventions
BIOLOGICAL

AK111

AK111 administered subcutaneously at Week 0, 1, and 4, then every 4 weeks

BIOLOGICAL

Placebo

Placebo administered subcutaneously at Week 0, 1, and 4, then every 4 weeks

Trial Locations (15)

Unknown

The first affiliated hospital of Bengbu medical college, Bengbu

Peking university people's hospital, Beijing

Peking University Shougang hospital, Beijing

Peking University Third Hospital, Beijing

Xuanwu hospital capital medical university, Beijing

Guangdong provincial people's hospital, Guangzhou

Nanfang Hospital, Guangzhou

The first affiliated hospital of Zhengzhou University, Zhengzhou

Jiangsu Province Hospital, Nanjing

Nanjing Drum Tower hospital, Nanjing

Zhongda Hospital Southeast University, Nanjing

The First Affiliated Hospital of Nanchang University, Nanchang

The first Bethune hospital of Jilin university, Changchun

Second hospital of Shanxi Medical university, Taiyuan

The seventh affiliated hospital, Sun Yat-sen university, Shenzhen

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Akeso

INDUSTRY

NCT05467995 - A Study to Evaluate the Efficacy and Safety of AK111 in Subjects With Active Ankylosing Spondylitis | Biotech Hunter | Biotech Hunter