2,480
Participants
Start Date
July 5, 2022
Primary Completion Date
February 28, 2026
Study Completion Date
February 28, 2026
Carotid Endarterectomy
This is the standard proven therapy for carotid stenosis that involves an arteriotomy followed by removal of plaque and reconstruction of the vessel.
FDA-approved carotid stents
This is the standard proven therapy for carotid stenosis that involves an arteriotomy followed by removal of plaque and reconstruction of the vessel.
Intensive Medical Management
INTERVENT risk factor management program to help manage patient's risk factors. The INTERVENT program will provide individualized risk factor counseling sessions (via telephone or internet) at regular interval by healthcare workers who are specially trained to help patients follow the medical management plan.
Weill Cornell Medical College, New York
Crouse Hospital, Syracuse
SUNY Buffalo, Buffalo
VA Pittsburgh, Pittsburgh
Yale New Haven Hospital, New Haven
Pinnacle Health, Harrisburg
Hospital of University of Pennsylvania, Philadelphia
Berks Cardiologists, Wyomissing
White Oak Medical Center, Silver Spring
VA Medical Center, Baltimore
Johns Hopkins University, Baltimore
Inova Fairfax Hospital, Falls Church
University of Virginia, Charlottesville
Wake Forest Baptist Health, Winston-Salem
Duke University Medical Center, Durham
Lyerly Neurosurgery/Baptist Health, Jacksonville
University of Florida Jacksonville, Jacksonville
Mayo Clinic Jacksonville, Jacksonville
Cardiovascular Institute NW Florida, Panama City
University of Florida Health at Shands, Gainesville
Miami Cardiac and Vascular Institute, Miami
Morton Plant Mease Healthcare, Clearwater
University of Alabama at Birmingham, Birmingham
Wellmont CVA Heart Institute, Kingsport
Tennova Healthcare, Knoxville
Baptist Health, Lexington
Mercy Health St. Vincent, Toledo
Deaconess Heart Group, Newburgh
VA Ann Arbor, Ann Arbor
Michigan Heart, Ypsilanti
Henry Ford Health System, Detroit
Michigan Vascular Center, Flint
Sparrow Clinical Research Institute, Lansing
University of Iowa Hospitals & Clinics, Iowa City
Gundersen Clinic, Ltd., La Crosse
North Memorial Medical Center, Golden Valley
Mayo Clinic Rochester, Rochester
Endeavor Health/NorthShore University, Evanston
University of Chicago Medical Center, Chicago
Prairie Heart/St. John's Hospital, Springfield
Mercy Hospital, St Louis
Ochsner Health System, New Orleans
Central Arkansas VA, Little Rock
Seton Medical Center, Austin
University of Utah Hospitals & Clinics, Salt Lake City
Mayo Clinic Pheonix, Phoenix
Banner University Medical Center, Tucson
Kaiser Permanente Los Angeles, Los Angeles
USC/Keck Medical Center, Los Angeles
University of California Los Angeles, Los Angeles
Kaiser Permanente Divsion of Research, San Francisco
Kaiser Permanente San Francisco, San Francisco
Mission Cardiovascular Research Institute, Fremont
St. Joseph's Medical Center, Stockton
Oregon Health & Science University, Portland
VA Puget Sound, Seattle
Hartford Hospital, Hartford
Maine Medical Center, Portland
Massachusetts General Hospital, Boston
St. Elizabeth's Medical Center, Boston
The Miriam Hospital, Providence
Vancouver General Hospital, Vancouver
Nova Scotia Health Authority, Halifax
Hospital Clinic of Barcelona, Barcelona
Lead Sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
University of Alabama at Birmingham
OTHER
University of Maryland
OTHER
Medical University of South Carolina
OTHER
Mayo Clinic
OTHER