Tislelizumab Combined with Mitoxantrone Hydrochloride Liposome in Extranodal Natural Killer/T Cell Lymphoma

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

June 23, 2022

Primary Completion Date

April 30, 2025

Study Completion Date

November 30, 2025

Conditions
Extranodal Natural Killer T Cell Lymphoma
Interventions
DRUG

Tislelizumab combined with Liposomal mitoxantrone hydrochloride

"Drug: liposomal mitoxantrone hydrochloride, tislelizumab Drug: Liposomal mitoxantrone hydrochloride (16 mg/m2, 20 mg/m2) will be administered by an intravenous infusion on day 1 of each 28-day cycle.~Drug: tislelizumab(200 mg) will be taken orally on day 1 of each 28-day cycle."

DRUG

Maintenance of tislelizumab

Drug: tislelizumab(200 mg) will be taken orally on day 1 of each 21-day cycle

Trial Locations (6)

Unknown

Beijing Tongren Hospital, Capital Medical University, Beijing

Peking Union Medical College Hospital, Beijing

The Second Hospital of Dalian Medical University, Dalian

Sun Yat-Sen University Cancer Center, Guangzhou

The First Affiliated Hospital/School of Clinical Medicine of Guangdong Pharmaceutical University, Guangzhou

Jiangxi Cancer Hospital, Nanchang

All Listed Sponsors
lead

Sun Yat-sen University

OTHER