Liquid Biopsy for Early Non-small Lung Cancer Detection

CompletedOBSERVATIONAL
Enrollment

171

Participants

Timeline

Start Date

August 2, 2022

Primary Completion Date

March 22, 2024

Study Completion Date

March 22, 2024

Conditions
Non Small-cell Lung Cancer
Interventions
DIAGNOSTIC_TEST

Liquid biopsy for aberrant DNA methylation analysis - Indeterminate pulmonary nodule

10 cc of blood is collected at one time point, which is prior to biopsy procedure

DIAGNOSTIC_TEST

Liquid biopsy for aberrant DNA methylation analysis - Known lung cancer for surgical resection

10 cc of blood is collected at three time points: 1) before surgery; 2) 4-6 weeks post surgery; and 3) 6 months post surgery

DIAGNOSTIC_TEST

Liquid biopsy for aberrant DNA methylation analysis - Healthy volunteer

10 cc of blood is collected at one time point

DIAGNOSTIC_TEST

Liquid biopsy for aberrant DNA methylation analysis - Benign lung disease

30 cc of blood is collected at one time point

Trial Locations (1)

85724

University of Arizona, Tucson

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

University of Arizona

OTHER