Pilot Study Comparing the Safety and Efficacy of Two Dosing Regimens of TP-03 for the Treatment of MGD

PHASE2CompletedINTERVENTIONAL
Enrollment

39

Participants

Timeline

Start Date

August 3, 2022

Primary Completion Date

May 18, 2023

Study Completion Date

May 18, 2023

Conditions
Meibomian Gland DysfunctionBlepharitisDemodex Infestation
Interventions
DRUG

TP-03

TP-03, lotilaner ophthalmic solution, 0.25%, administered twice a day in participants in the BID dosing arm and three times a day in participants in the TID dosing arm

DRUG

TP-03 Vehicle

Vehicle of TP-03 ophthalmic solution, administered once a day in participants in the BID dosing arm to maintain masking between arms

Trial Locations (5)

17349

Medical Optometry America, New Freedom

27513

Oculus Research, Cary

28150

CORE Inc., Shelby

64133

Silverstein Eye Center, Kansas City

91325

Mitchell C. Shultz, MD, Northridge

All Listed Sponsors
lead

Tarsus Pharmaceuticals, Inc.

INDUSTRY