KM-001 Cream for Treatment of Pruritus in Adult Patients With Lichen Simplex Chronicus (LSC)

KM-001 will be supplied in glass jars (30 ml) and will be provided to patients with spatulas and polyethylene gloves on all the clinical visits. the patient will use IMP twice a day for 28 days.

patients will provide a blood sample for a chemistry blood test on days -14 (screening visit), Day 7(visit 3), day 28 (end of treatment) or at ET visit.

patients will provide a blood sample for a hematology blood test on days -14 (screening visit), Day 7(visit 3), day 28 (end of treatment) or at ET visit.

Patients will provide a blood sample for a urine test on days -14 (screening visit), Day 7(visit 3), day 28 (end of treatment) or at ET visit.

Patients will provide a blood sample for serelogy test at day -14 (screening visit)

patients will undergo an ECG examination on days -14 (screening visit), and day 28 (end of treatment visit).

Women of child-bearing potential only will provide at all the on-site visits b-hCG concentration will be tested

PK test will be performed on day 1, 7, 28, 35 and on ET visit

patients will undergo a physical examination on all the clinical visits

patient's vital signs will be measured on all the clinical visits

patient's disease evaluations will be evaluated on all the clinical visits

patient's disease evaluations will be evaluated on all the clinical visits

The patient will record IMP adminidsration and AE events in a diary every day throughout the all study period