Aciclovir Versus Placebo for HSV-2 Meningitis

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

June 1, 2026

Primary Completion Date

June 1, 2028

Study Completion Date

June 1, 2029

Conditions
Herpes Simplex 2Meningitis, Viral
Interventions
DRUG

Acyclovir 50 MG/ML

Patients are randomised to active treatment with IV acyclovir with the possibility of step-down to valacyclovir. If the treating physician prefers, initial IV treatment can be omitted and the patient can be treated with valacyclovir throughout the study period.

DRUG

Placebo

Placebo either in IV formulation or as tablets identical to valacyclovir tablets.

All Listed Sponsors
lead

Jacob Bodilsen

OTHER