Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

37

Participants

Timeline

Start Date

July 19, 2022

Primary Completion Date

August 31, 2027

Study Completion Date

November 30, 2027

Conditions
Small-cell Lung CancerSmall Cell Lung Carcinoma
Interventions
DRUG

Onvansertib

Onvansertib at a dose of 15 mg/m2 orally on Days 1-14 of a 21-day cycle. Treatment will continue until disease progression or intolerable toxicity.

Trial Locations (2)

15232

ACTIVE_NOT_RECRUITING

UPMC Hillman Cancer Center, Pittsburgh

21201

RECRUITING

University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Cardiff Oncology

INDUSTRY

collaborator

National Cancer Institute (NCI)

NIH

lead

Taofeek Owonikoko

OTHER