ONC-392 and Pembrolizumab in Platinum Resistant Ovarian Cancer

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

58

Participants

Timeline

Start Date

December 22, 2022

Primary Completion Date

October 30, 2025

Study Completion Date

June 30, 2026

Conditions
Ovarian CancerHigh Grade Serous Adenocarcinoma of OvaryPrimary Peritoneal CarcinomaFallopian Tube Cancer
Interventions
DRUG

ONC-392

ONC-392 will be given by IV infusion, q3w.

DRUG

Pembrolizumab

Pembrolizumab in fixed dose of 200 mg will be given by IV infusion, q3w.

Trial Locations (21)

12208

Women's Cancer Care Associates, LLC. 405, Albany

32207

Baptist MD Anderson Cancer Center, 404, Jacksonville

40207

Norton Cancer Institute - St. Matthews, 416, Louisville

40503

Baptist Health Lexington, 407, Lexington

43210

The Ohio State University James Cancer Center, 412, Columbus

46311

Northwest Cancer Centers - Dyer, IN - USOR, 422, Dyer

53226

Medical College of Wisconsin, 408, Milwaukee

55109

Minnesota Oncology Hematology, P. A. - USOR, 421, Maplewood

60099

Cancer Treatment Centers of America, Chicago. 410, Zion

60521

Sudarshan Sharma, MD. LTD. 414, Hinsdale

71103

Willis-Knighton Physician Network / Gynecologic Oncology Associates, 409, Shreveport

75702

Texas Oncology - Northeast Texas - USOR, 423, Tyler

76104

Texas Oncology, P.A., Fort Worth - USOR. 420, Fort Worth

77380

Texas Oncology, P. A. Woodlands - USOR, 418, The Woodlands

78731

Texas Oncology, P. A. - Austin, USOR. 417, Austin

85082

Honor Health, USOR, 406, Phoenix

85338

Cancer Treatment Centers of America, Phoenix. 403, Goodyear

89511

Center of Hope, 413, Reno

97401

Oncology Associates of Oregon, P. C. - USOR. 419, Eugene

06856

Nuvance Health System, 401, Danbury

07450

The Valley Hosptial, Inc. 411, Ridgewood

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

collaborator

GOG Foundation

NETWORK

lead

OncoC4, Inc.

INDUSTRY

NCT05446298 - ONC-392 and Pembrolizumab in Platinum Resistant Ovarian Cancer | Biotech Hunter | Biotech Hunter