Durvalumab and Tremelimumab in Resectable HCC

PHASE2RecruitingINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

October 26, 2023

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2026

Conditions
Hepatocellular Carcinoma
Interventions
DRUG

Tremelimumab

Pre-operatively Tremelimumab will be administered first for 1 hour; the Durvalumab infusion (1hr) will start approximately 1 hour (maximum 2 hours) after the end of the Tremelimumab infusion. Post-operatively patients will receive Durvalumab Q4W to complete up to 12 months of treatment or a maximum of 11 cycles of adjuvant Durvalumab

Trial Locations (3)

20122

NOT_YET_RECRUITING

University of Milan, Milan

31008

NOT_YET_RECRUITING

Clinica Universidad De Navarra, Pamplona

M5G 2M9

RECRUITING

University Health Network, Toronto

All Listed Sponsors
collaborator

Clinica Universidad de Navarra, Universidad de Navarra

OTHER

collaborator

University of Milan

OTHER

lead

University Health Network, Toronto

OTHER