An Expanded Clinical Study of Triple Therapy for Refractory Solid Tumors That Failed First-line Treatment for Recurrence and Metastasis

NAUnknownINTERVENTIONAL
Enrollment

195

Participants

Timeline

Start Date

November 1, 2021

Primary Completion Date

October 1, 2023

Study Completion Date

October 31, 2023

Conditions
Advanced CancerMetastatic Cancer
Interventions
BIOLOGICAL

Autologous Adoptive immune cells

Immunotherapy Mononuclear cells were collected from 50ml peripheral blood , and cultured adoptive immune cells for 15-20 days. Cells were infused back to the patients in 3 times via intravenous infusion.

DEVICE

Thermotron RF-8EX

Hyperthermia for 40-50 minutes

DRUG

Chemotherapy,checkpoint immunotherapy, targeted therapy

The doctor chooses the appropriate systemic treatment for the patient based on NCCN guidelines

Trial Locations (1)

201399

RECRUITING

Fudan University Pudong Medical Center, Shanghai

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Duke University

OTHER

lead

Shanghai Pudong Hospital

OTHER

NCT05438342 - An Expanded Clinical Study of Triple Therapy for Refractory Solid Tumors That Failed First-line Treatment for Recurrence and Metastasis | Biotech Hunter | Biotech Hunter