Effects of Blood-flow Restricted Exercise Compared to Standard Rehabilitation in Patients With Knee Osteoarthritis

NACompletedINTERVENTIONAL
Enrollment

96

Participants

Timeline

Start Date

January 1, 2022

Primary Completion Date

January 15, 2025

Study Completion Date

February 14, 2025

Conditions
Osteoarthritis, Knee
Interventions
OTHER

BFR (Blood-Flow Restricted exercise)

The BFR group performs unilateral training with the knee-OA diagnosed leg first. BFR exercise is performed with a pneumatic cuff placed at the top of the thigh on the leg being trained. The cuff will be inflated to 60-80 % of the total arterial occlusion pressure (AOP). The participant will afterwards perform training of the knee extensors in a leg press exercise machine and a leg extension exercise machine with a load corresponding to 30 % of the maximal load (1RM = Repetition Maximum).

OTHER

Standard rehabilitation

The GLA:D programme involves a circuit training program with four stations. Each station involves two to six exercises where the participants perform 10-15 repetitions over 2-3 sets, which depends on the participants pain- and functional level. Following the 8 weeks GLA:D programme, participants will continue 4 weeks of team group training performing similar neuromuscular lower limb exercises as for the first 8 weeks.

Trial Locations (1)

2400

Department of Physical and Occupational Therapy / Institute of Sports Medicine Copenhagen, Bispebjerg Hospital, Copenhagen

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

University of Southern Denmark

OTHER

collaborator

Gigtforeningen

OTHER

collaborator

Sygekassernes Helsefond

OTHER

collaborator

AP Moeller Foundation

OTHER

collaborator

Aase and Ejnar Danielsens Foundation

OTHER

collaborator

Praksisfonen

UNKNOWN

collaborator

FAPS

UNKNOWN

lead

Bispebjerg Hospital

OTHER