Fruquintinib Combined With Tislelizumab and HAIC in Patients With Advanced Colorectal Liver Metastases Cancer Who Failed Standard Therapy

After successful percutaneous hepatic artery cannulation, superior mesenteric arteriogram and hepatic arteriogram were performed, and after confirming that the subjects were eligible for enrollment according to the results, the hepatic artery was cannulated to the predetermined position. The catheter was connected to a syringe pump in the ward for continuous pumping of drugs.

3mg, qd, po, 21 days for a cycle, Suspend medication on the day of HAIC

200mg, ivgtt, d1, 21 days for a cycle

2 mg/m2, hepatic artery infusion for 15 min, d1, 4-6 Cycles

85 mg/m2, hepatic artery infusion for 2 h, d1, 4-6 Cycles

120mg/m2, hepatic artery perfusion for 30-90min, d1, 4-6 Cycles