Azacitidine in Combination With Low Dose Intensity Venetoclax in Patients With AML Incl. Explorative AML Profiling

PHASE2RecruitingINTERVENTIONAL
Enrollment

117

Participants

Timeline

Start Date

May 24, 2022

Primary Completion Date

September 1, 2031

Study Completion Date

September 1, 2031

Conditions
Acute Myeloid Leukemia
Interventions
DRUG

Venetoclax

"Standard azacytidine treatment (AZA; D1-D7, 75mg/m2 qd) in combination with a short duration of low-dose venetoclax treatment (LD-VEN; D1-D14 before CR and D1-D7 after CR, 400mg qd) per 28 days cycle for elderly/unfit (arm 1) and relapsed/refractory (arm 2) patients with acute myeloid leukemia."

Trial Locations (1)

2100

RECRUITING

Department of Hematology, Rigshospitalet, Copenhagen

All Listed Sponsors
collaborator

Helse Stavanger HF

OTHER_GOV

collaborator

University Hospital of North Norway

OTHER

collaborator

Haukeland University Hospital

OTHER

collaborator

St. Olavs Hospital

OTHER

collaborator

Vestre Viken Hospital Trust

OTHER

collaborator

Helse Møre og Romsdal HF

OTHER_GOV

collaborator

Karolinska University Hospital

OTHER

collaborator

Skane University Hospital

OTHER

collaborator

Uppsala University Hospital

OTHER

collaborator

Helsinki University Central Hospital

OTHER

collaborator

Oulu University Hospital

OTHER

collaborator

Tampere University Hospital

OTHER

collaborator

Kuopio University Hospital

OTHER

lead

Rigshospitalet, Denmark

OTHER