NCT05430334View on ClinicalTrials.gov

Assess the Influence of Nicotine Flux and Nicotine Form on Subjective Effects Related to Dependency

NACompletedINTERVENTIONAL
Enrollment

130

Participants

Timeline

Start Date

July 13, 2022

Primary Completion Date

July 11, 2025

Study Completion Date

July 11, 2025

Conditions
Nicotine VapingNicotine DependenceNicotine Addiction
Interventions
COMBINATION_PRODUCT

e-liquid 1

30/70 PG/VG ratio with nicotine concentration 4mg/ml protonated

COMBINATION_PRODUCT

e-liquid 2

30/70 PG/VG ratio with nicotine concentration 10mg/ml protonated

COMBINATION_PRODUCT

e-liquid 3

30/70 PG/VG ratio with nicotine concentration 4mg/ml free base

COMBINATION_PRODUCT

e-liquid 4

30/70 PG/VG ratio with nicotine concentration 10mg/ml freebase

COMBINATION_PRODUCT

e-liquid 5

30/70 PG/VG ratio with nicotine concentration 0mg/ml (placebo)

COMBINATION_PRODUCT

e-liquid 6

30/70 PG/VG ratio with nicotine concentration 0mg/ml

COMBINATION_PRODUCT

e-liquid 7 and e-liquid 8

e-liquid 7: 30/70 PG/VG ratio with nicotine concentration 4mg/ml protonated e-liquid 8: 30/70 PG/VG ratio with nicotine concentration 8mg/ml protonated

COMBINATION_PRODUCT

e-liquid 9 and e-liquid 10

e-liquid 9: 30/70 PG/VG ratio with nicotine concentration 4mg/ml protonated e-liquid 10: 70/30 PG/VG ratio with nicotine concentration 4mg/ml protonated

Trial Locations (1)

11-0236

American University of Beirut, Beirut

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

American University of Beirut Medical Center

OTHER