Metabolic Pathology of Pediatric NAFLD

NARecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

May 25, 2022

Primary Completion Date

February 28, 2026

Study Completion Date

June 30, 2026

Conditions
Nonalcoholic Fatty LiverNonalcoholic SteatohepatitisObesity
Interventions
OTHER

Oral sugar tolerance test

Measurement of glucose and insulin for calculation of insulin sensitivity

OTHER

De novo lipogenesis test

Oral consumption of deuterated water to measure incorporation of label into lipids

OTHER

Gluconeogenesis test

Oral consumption of 13C-labeled glycerol to measure incorporation into glucose

Trial Locations (1)

73104

RECRUITING

University of Oklahoma Health Sciences Center, Oklahoma City

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

University of Oklahoma

OTHER